Magnus Unemo Selected Research

Gonorrhea

1/2022	Gentamicin Susceptibility in Neisseria gonorrhoeae and Treatment Outcomes for Urogenital Gonorrhea After 25 Years of Sustained Gentamicin Use in Malawi.
1/2022	Pharmacodynamic Evaluation of Zoliflodacin Treatment of Neisseria gonorrhoeae Strains With Amino Acid Substitutions in the Zoliflodacin Target GyrB Using a Dynamic Hollow Fiber Infection Model.
1/2021	Serum Complement Activation by C4BP-IgM Fusion Protein Can Restore Susceptibility to Antibiotics in Neisseria gonorrhoeae.
1/2021	Pharmacodynamic Evaluation of Dosing, Bacterial Kill, and Resistance Suppression for Zoliflodacin Against Neisseria gonorrhoeae in a Dynamic Hollow Fiber Infection Model.
1/2020	Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics.
9/2019	High in vitro susceptibility to the first-in-class spiropyrimidinetrione zoliflodacin among consecutive clinical Neisseria gonorrhoeae isolates from Thailand (2018) and South Africa (2015-2017).
1/2019	Quantitative Proteomics of the 2016 WHO Neisseria gonorrhoeae Reference Strains Surveys Vaccine Candidates and Antimicrobial Resistance Determinants.
1/2019	Antimicrobial Resistance in Neisseria gonorrhoeae and Treatment of Gonorrhea.
1/2019	Pharmacokinetic Data Are Predictive of In Vivo Efficacy for Cefixime and Ceftriaxone against Susceptible and Resistant Neisseria gonorrhoeae Strains in the Gonorrhea Mouse Model.
1/2018	In Vivo-Selected Compensatory Mutations Restore the Fitness Cost of Mosaic penA Alleles That Confer Ceftriaxone Resistance in Neisseria gonorrhoeae.

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Magnus Unemo Research Topics

Disease

45	Infections 06/2022 - 02/2002
36	Gonorrhea 01/2022 - 09/2009
21	Sexually Transmitted Diseases (Sexually Transmitted Disease) 01/2022 - 03/2011
5	Urethritis 11/2018 - 08/2011
4	Syphilis 12/2021 - 01/2015
4	Hypersensitivity (Allergy) 09/2019 - 01/2018
3	Reproductive Tract Infections 01/2022 - 09/2010
2	Vaginal Discharge 12/2018 - 06/2014
2	Uterine Cervicitis (Cervicitis) 02/2018 - 08/2011
2	Prostatic Neoplasms (Prostate Cancer) 01/2016 - 08/2012
2	Meningococcal Infections 01/2010 - 03/2009
1	Vomiting 01/2022
1	Nausea 01/2022
1	Proctitis 01/2022
1	Drug-Related Side Effects and Adverse Reactions 01/2019
1	Inflammation (Inflammations) 01/2019
1	Body Weight (Weight, Body) 01/2019
1	Cicatrix (Scar) 12/2018
1	Pelvic Inflammatory Disease (Pelvic Inflammatory Diseases) 12/2018
1	Chlamydia Infections 12/2018
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2018
1	Disease Progression 03/2017
1	Persistent Infection 03/2017
1	Bacterial Vaginosis 01/2017
1	Ulcer 07/2016
1	secondary Syphilis 07/2016
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2016
1	Trichomonas Infections 01/2015
1	Surgical Wound Infection 10/2014

Drug/Important Bio-Agent (IBA)

21	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 01/2022 - 07/2011
18	Azithromycin (Zithromax)FDA LinkGeneric 06/2022 - 08/2011
12	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 02/2002
11	Cephalosporins (Cephalosporin Antibiotics)IBA 01/2020 - 09/2009
10	VaccinesIBA 01/2020 - 03/2009
8	Ciprofloxacin (Cipro)FDA LinkGeneric 06/2022 - 01/2010
8	zoliflodacinIBA 01/2022 - 09/2014
7	MacrolidesIBA 12/2021 - 02/2015
6	Pharmaceutical PreparationsIBA 01/2021 - 12/2012
5	Cefixime (Suprax)FDA Link 03/2021 - 03/2012
5	Nucleic AcidsIBA 06/2020 - 09/2010
5	AntigensIBA 01/2019 - 01/2003
4	Gentamicins (Gentamicin)FDA LinkGeneric 01/2022 - 03/2011
4	Moxifloxacin (Avelox)FDA Link 01/2020 - 10/2012
4	FluoroquinolonesIBA 01/2019 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 12/2019
3	Rifampin (Rifampicin)FDA LinkGeneric 04/2015 - 09/2010
3	Penicillin G (Benzylpenicillin)FDA LinkGeneric 04/2015 - 01/2010
2	DNA GyraseIBA 01/2022 - 01/2021
2	Penicillins (Penicillin)FDA Link 01/2022 - 01/2016
2	Doxycycline (Periostat)FDA LinkGeneric 06/2021 - 04/2015
2	sitafloxacinIBA 01/2018 - 01/2018
2	Anti-Infective Agents (Microbicides)IBA 12/2017 - 04/2015
2	Clindamycin (Cleocin)FDA LinkGeneric 04/2015 - 10/2012
2	Linezolid (Zyvox)FDA Link 04/2015 - 10/2012
2	Fusidic Acid (Fucithalmic)IBA 04/2015 - 10/2012
2	Metronidazole (Metric)FDA LinkGeneric 04/2015 - 10/2012
2	solithromycinIBA 06/2014 - 05/2012
1	Amino Acids FDA Link 01/2022
1	Contraceptive Agents (Contraceptives)IBA 01/2022
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2022
1	Membrane Transport Proteins (Biological Pump)IBA 01/2022
1	Virulence Factors (Pathogenicity Factors)IBA 01/2022
1	Auranofin (Ridaura)FDA Link 03/2020
1	ProteomeIBA 01/2019
1	SolutionsIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 12/2018
1	gepotidacinIBA 01/2018
1	Capsules (Microcapsules)IBA 12/2017
1	AcidsIBA 03/2017
1	Cholera ToxinIBA 12/2016
1	23S Ribosomal RNAIBA 07/2016
1	SulfonamidesIBA 01/2016
1	Cytidine Monophosphate (CMP)IBA 12/2015
1	Josamycin (EN 141)IBA 02/2015
1	Topoisomerase II InhibitorsIBA 01/2015
1	Local Anti-Infective Agents (Antiseptics)IBA 10/2014
1	A-Form DNA (A-DNA)IBA 09/2014
1	Biological ProductsIBA 07/2014
1	Spectinomycin (Spectinomycin Hydrochloride)FDA Link 02/2013
1	antiarrhythmic peptide (AAP)IBA 01/2013
1	Imipenem FDA Link 10/2012
1	Vancomycin FDA LinkGeneric 10/2012
1	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 10/2012
1	Daptomycin FDA Link 10/2012
1	Tigecycline (Tygacil)FDA Link 10/2012
1	Tetracycline (Achromycin)FDA LinkGeneric 10/2012
1	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 10/2012
1	Erythromycin (Erycette)FDA LinkGeneric 10/2012
1	Ertapenem (Invanz)FDA Link 07/2012
1	Cefotaxime (Kendrick)FDA LinkGeneric 03/2012
1	AgarIBA 03/2011
1	CytokinesIBA 09/2010

Therapy/Procedure

10	Therapeutics 01/2020 - 07/2012
2	Aftercare (After-Treatment) 01/2017 - 01/2016
1	Prostatectomy (Retropubic Prostatectomy) 01/2016
1	Intravaginal Administration 12/2015
1	Prenatal Care (Care, Prenatal) 01/2015
1	Injections 12/2013
1	Dermatologic Surgical Procedures 08/2012
1	Condoms (Condom) 05/2011